Propylene Glycol or Vegetable Glycerin for e-Juice. What's the Difference?

The Difference Between
Vegetable Glycerin and Propylene Glycol for Vaping

We’re going to explain the differences between the two most widely used vape liquid bases: Propylene Glycol (PG) and Vegetable Glycerin (VG).

The base, or carrier, holds the nicotine and flavor in suspension so your e-cigarette or vaporizer can produce thick clouds when exhaling.

Both propylene glycol and vegetable glycerin are non-toxic, organic compounds and are generally considered safe for consumption by the FDA. In fact, they are widely used as food additives in a variety of commercially available food and personal care products.

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Vegetable Glycerin

Thick Consistency

Vegetable glycerin is a much thicker solution compared to propylene glycol. It has a slower absorption rate for wicks and cartomizers. However, this can cause issues clogging up vape mechanisms which may require frequent cleaning.

Sweeter Taste

On its own, vegetable glycerin has a slightly sweet taste naturally, which also makes the e-liquid sweeter and the flavors more difficult to detect.

Less 'Throat Hit'

For those who want a smoother vape experience, vegetable glycerin-based vape juice is smoother and delivers less of a ‘throat hit’ compared to PG.

Thicker Vape Clouds

Vegetable Glycerin e-liquids produce significantly more vapor because of their thicker consistency and don’t cause allergic reactions or irritations as often as propylene glycol.

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Propylene Glycol

Thinner Consistency

Propylene glycol is less viscous, and has a runny consistency. Liquids containing propylene glycol are thinner than the vegetable glycerin variety, and are easily absorbed by cartomizers and wick tanks.

True Flavors

Propylene glycol is a tasteless, odorless substance, so it doesn’t alter the flavor of the flavor concentrates in any way.

Stronger 'Throat Hit'

Propylene Glycol will dry out your mouth and throat if used consistently. PG also produces a stronger throat hit, similar to that of tobacco cigarettes.


Propylene glycol has been known to cause allergic reactions to some users. These can vary from minor reactions, like a tingling sensation in the throat, to serious irritations on various parts of the body.

How to Choose Between Propylene Glycol or Vegetable Glycerin?

Propylene glycol e-liquid tend to deliver a better throat hit and a more flavor for vaping. Vegetable glycerin allows atomizers to produce thicker vape clouds. The vaping community is evenly divided when it comes to e-liquid preference. Some enjoy the intense throat hits more than flavor and vapor, others enjoy the sweet, thick plumes of vapor. At Delosi Labs, we suggest starting with a liquid containing a slightly higher vegetable glycerin blend — 60% or 70% VG. The most common PG/VG ratio in retail e-liquids contain a 30/70 ratio — containing 70% vegetable glycerin.

Which is Safer?

Both Vegetable Glycerin and Propylene Glycol are used in a variety of foods that you consume on a daily basis, and are deemed safe by the FDA. However, in some small cases, people have experienced allergic reactions to propylene glycol; the most common is skin irritation.